It seems to me that a beginning adventure could be written that involves a AG colony where bad stuff has happened and PCs start out as colonist or recent visitors. Farm equipment is plentiful and available for free- twist on Crash on Volturnus where PCs have limited resources and must improvise. HVy duty at robots available for roboticist to work on, fertilizer sprayer could be adapted as weapon, sonic prods, my SCARECROW bot as potential malfunctioning adversay. Ect. 

Start is that bad thing has happened so PCs are emerging from after math which gives you a "en media res" beginning like Crash on V. This bad thing needs to be really bad so that it's completely understandable that any colonist PCs opt to leave rather than rebuild. 

Potential : locals Are any colony with AG economy. New Pale, Rupert's Hole and Lossend stand out in my memory but a new colony let's you start with a clean slate. 

Potential bad things: Sathar attack, pirate attack, xenomorph & Face huggers, natural disaster. Corporate aggression. Or ?

This is a brainstorm thread feel free to suggest ideas. Title is working title.